Tuesday, 17 July 2018

Several 3D cell culture options are available in the form of scaffold-based, scaffold-free, and 3D bioreactor systems

The global 3D cell culture market size is expected to reach USD 1.69 billion by 2024, exhibiting a 14.8% CAGR during the forecast period. Need to incorporate 3D cell culture systems in research for better representation of in vivo environment has driven development of new materials and methods, thereby propelling market growth.

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3D cell culture is more suitable for in vivo modeling due to the resemblance they provide to morphology of organ or cells. Several 3D cell culture options are available in the form of scaffold-based, scaffold-free, and 3D bioreactor systems. Emergence of 3D optimized assays, kits, and protocols, along with maturity in development of different assay techniques, is projected to accelerate market growth.

Increasing adoption of tissue engineering and organ transplantation for chronic diseases is projected to drive adoption in research over the forecast period. Furthermore, use of microchips to implement culturing through use of micro-fabricated tissue component is expected to present the market with potential avenues.

Fabrication techniques to produce scaffold-free systems that are inexpensive, transparent, and compatible with liquid handling tools have emerged. Rapid adoption of these systems for tissue engineering research, drug discovery, and personalized medicine contributes to market growth. Scaffold-free technology is expected to observe the fastest growth over the next few years, registering an estimated CAGR of around 15.7% from 2016 to 2024.

Further key findings from the report suggest:
  • Emergence of novel fabrication techniques contributes to the growth of scaffold-free 3D cell culture systems
  • Rapid adoption of culturing systems in cancer research for development of immortalized established cell lines or primary cell cultures to perform in vivo drug screening has led to its largest revenue share
  • 3D bioprinting enables creation of 3D printed building blocks of embryonic stem cells, which could be further used for micro-organ generation and tissue regeneration experiments
  • Changing of regulatory policies for stem cell research and high potential of 3D culturing tools fuels the stem cell research segment
  • North America dominated the global 3D cell culture market with a share of over 41.0% in 2016. Presence of major pharma and biotech players that collaborate with research laboratories to implement these technologies drives progress in U.S.
  • Asia Pacific is projected to witness substantial growth over the forecast period owing to rapid developments across major economies, especially in the tissue engineering and stem cell research domain. APAC is expected to exhibit a CAGR of 16% during the forecast period
  • Key players include Merck, 3D Biotek LLC; 3D Biomatrix; Nano3D Biosciences Corning Inc.; VWR International, LLC; Thermo Fisher Scientific; Global Cell Solutions, Inc.; Becton Dickinson and Company; Tecan; InSphero AG; and Lonza Group
  • Major players focus on collaborating with laboratories to commercialize technologies that are not potentially established in the market space.
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Muscle stimulator market size is progressing at a CAGR of 4.2% by 2025

The global muscle stimulator market size is expected to reach USD 853.09 million by 2025, progressing at a CAGR of 4.2% during the forecast period. Increasing number of patients suffering from chronic pain and rising healthcare spending in emerging countries are among the key trends stimulating the growth of the market.
 
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Physiotherapists are increasingly shifting their preference from manual techniques to muscle stimulation devices, such as transcutaneous electrical nerve stimulation (TENS), and galvanic electrical stimulation to treat patients in clinical or home care settings. These muscle stimulation devices generate therapeutic currents that are useful for rehabilitation of muscles after an injury.

Anterior cruciate ligament (ACL) tear, hip flexor strains, and hamstring strains are some of the most common sports injuries that require muscle stimulation therapy. With increasing incidence of these muscle injuries among sportspersons, demand for muscle stimulators is projected to increase, thereby escalating the growth of the market.

Moreover, in several developed countries, musculoskeletal disorders is one of the key causes of physical disability. As per the statistics provided by the Arthritis Research U.K., about 35.2% of people in the U.K. were affected by musculoskeletal disorders in 2017. Such factors are estimated to bolster the growth of the market.

Further key findings from the report suggest:
  • Transcutaneous electrical nerve stimulation is poised to exhibit a CAGR of 3.8% from 2017 to 2025
  • Portable muscle stimulation devices dominated the market with a market share of over 35.0% in 2016 and are anticipated to witness a CAGR of 4.6% during the forecast period
  • Pain management dominated the market with a valuation of USD 316.13 million in 2016 and is likely to expand at a CAGR of 4.4% during the forecast period
  • Physiotherapy clinics dominated the market in 2016 and are expected to witness the highest CAGR of 4.9% during the same period
  • Asia Pacific is estimated to witness a CAGR of 5.4% over the forecast period, owing to soaring need for better diagnostic devices and mounting cases of sports injuries
  • Some of the prominent companies operating in the market are DJO Global, Inc.; Zynex, Inc.; NeuroMetrix, Inc.; RS Medical, Inc.; OMRON Corporation; Zimmer MedizinSysteme GmbH; BioMedical Life Systems, Inc.; EMS Physio Ltd.; Beurer GmbH; and OG Wellness Technologies Co., Ltd.
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Industrial hemp market size is expected to reach USD 10.6 billion by 2025

The global industrial hemp market size is expected to reach USD 10.6 billion by 2025. The market is anticipated to expand at a CAGR of 14.0% during the forecast period. Rising demand for oil in food and beverages owing to growing awareness regarding dietary advantages of hemp-seed and oil is expected to propel demand.

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Growing population and rising disposable income are expected to result in an increased demand for high-quality cosmetics, personal care products, protein supplements, and other health food products. These factors are expected to be key driving factors for the market over the projected period.

Increasing R&D activities to develop perfect agronomy and new genetics of crops to obtain high yield and improved product quality have a positive impact on hemp production. Companies in the market operate with fiber treatment technology to make fibers water repellant, fire retardant, absorptive, and super soft, which is expected to drive demand.

Industrial hemp is an agricultural commodity and is highly dependent on climatic conditions, regulatory tolerance, and availability of labor. Countries such as China, the world's leading producer of the crop, have never restricted cultivation and have an advantage of inexpensive labor. However, oversupply is likely to be a major concern for manufacturers over the forecast period.

Further key findings from the report suggest:
  • By product, seeds accounted for 42.3% of the volume in 2017 owing to increasing demand for hemp grain to obtain seed, oil, and food matter due to its high fatty acid content and nutritional value
  • Product consumption in the textile industry is expected to witness a CAGR of 16.9%, in terms of revenue, from 2018 to 2025 due to strong, hypo-allergic, and UV light resistant characteristics of hemp fibers
  • The personal care industry accounted for 16.2% of the revenue in 2017 owing to high consumption of the crop oil in personal hygiene products including soap, shampoo, body lotions, and hair care products
  • The market in North America is expected to register a volume-based CAGR of 17.6% owing to rising product demand in the automotive industry for manufacturing panels and as an alternative to fiberglass
  • Major players in the industry focus on R&D activities to develop new varieties of the crop, full crop utilization, processing methods, and advanced technologies used for processing.

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Obesity is believed to be one of the foremost factors leading to diabetes in individuals

The global diabetes devices market size is expected to reach USD 35.5 billion by 2024. The market is projected to expand at a CAGR of 7.0% during the forecast period. Growing cases of diabetes, due to obesity, sedentary and unhealthy lifestyles, and several other factors, is expected to drive demand for diabetes devices over the next few years.

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Obesity is believed to be one of the foremost factors leading to diabetes in individuals. According to WHO, in 2014, over 1.9 billion people were identified to be overweight, of which, around 600 million people were obese.

Some of the key companies in the global diabetes devices market are Medtronic PLC, Sanofi S.A., Bayer Healthcare AG, Becton, Dickinson and Company, Novo Nordisk A/S, Abbott Laboratories, F. Hoffman-La Roche AG, and Johnson & Johnson.

Further key findings from the study suggest:
  • Constantly rising target population base is the primary factor driving market growth.
  • Test strips capturedthe largest share in the monitoring and diagnostics device segment while insulin pens accounted for the largest revenue share among insulin delivery devices in 2016. This can be attributed to rapid adoption of these user-friendly, quick, and accurate devices for homecare use.
  • North America is leading the regional market, followed by Europe. Advanced healthcare infrastructure and availability of technologically advanced products have driven the regional market.
  • Key players in the market include Medtronic PLC, Sanofi S.A., Bayer Healthcare AG, Becton Dickinson and Company, Novo Nordisk A/S, Abbott Laboratories, F. Hoffman-La Roche AG and Johnson & Johnson.
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Monday, 16 July 2018

The industry is highly consolidated in nature and is centered around five major players

The global gas turbine service market size is expected to reach USD 41.6 billion by 2025. The global market is anticipated to register a CAGR of 8.5% during the forecast period. Availability of natural gas in large quantities coupled with its relatively lower prices, especially in North America, China, and Thailand, has led to an increase in power generation using gas turbines. 

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The standby inspection (consist servicing of the relays cleaning, battery system, checking oil & water level and device calibration), running inspection, and combustion inspection (includes inspection of fuel nozzles and combustion liners) are the major maintenance and repair activities which are performed at different time interval, depending upon various factors such as operating hours, geographical condition, fuel, etc.

Growing focus on generating electricity through cleaner sources and discouragement of utilizing coal reserves are the factors anticipated to increase the share of gas turbines in the global energy mix. This, in turn, is expected to provide a favorable environment for the development of this market. One such strategy includes the recent orders passed by the current U.S. government to reverse the energy policies of the previous government and stop the war on coal, which is expected to boost the use of natural gas for energy production over the forecast period.

According to Diesel & Gas Turbine Worldwide, the total number of industrial gas turbines ordered in 2014 were 569 units, which increased to 581 in 2016. Of these, the total number of natural gas-fired industrial turbines, ranging from 30 MW to 120 MW, were 62 units in 2014 and reached 147 in 2016. Growth in industrial turbine installations across the globe is creating more opportunities for aftermarket services, which is building a favorable environment for the growth of gas turbine maintenance market.

Throughout their lifespan, the turbines undergo various inspections at different intervals. Combustor inspection (at 8,000-12,000 EOH), hot gas path inspection (at 24,000-50,000 EOH), and major inspection/overhaul (at 48,000-70,000 EOH) are some of the critical inspections that are essential for the reliable operation of gas turbines. Increasing utilization of gas turbines in resource extraction, processing applications, manufacturing facilities, and packaging plants is widening the product application scope, which is also projected to boost the aftermarket services for gas turbines. Increasing demand for the aftermarket services for gas turbine is projected to provide a substantial growth potential to the gas turbine service market.

Technological development in data collection methods is enabling players in this industry to form a constitutive model for materials. Test rig control helps in gathering and analyzing large volumes of data, thereby allowing players to create the most suitable maintenance plan and models for gas turbines.

Further key findings from the report suggest:
  • The global gas turbine service market was valued at USD 23.9 billion in 2017. The market is projected to witness a CAGR of 8.5% during the forecast period
  • The industry is highly consolidated in nature and is centered around five major players, which hold over 60% of the market
  • Early defect detection through the use of software and the preventive maintenance results in substantial cost saving, which has increased the importance of service providers in gas turbine market
  • Ease of maintenance and operation, higher efficiency, relatively lesser weight, and compatibility at offshore locations are some significant factors projected to drive the demand for <100 MW turbines
  • The key players include GE Power, Siemens AG, Mitsubishi Hitachi Power Systems, Ltd. (MHPS), Kawasaki Heavy Industries, Ltd., and MAN Diesel & Turbo SE.
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Friday, 13 July 2018

Advancements in genomics and associated technologies has significantly impacted crop genetics

The global genomics market is expected to reach USD 27.6 billion by 2025. The past decades have witnessed significant changes in disease management processes due to simultaneous advancements in genomics and personalized medicine. There has been a gradual growth in the usage of genomic studies in clinical practices, which is reflected by the growing trend of targeted therapies.

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Results from genomic studies enable a better understanding of diseases and the underlying mechanisms for researchers, physicians, and consumers. This facilitates evidence-based decision-making, and hence, helps improve personalized treatment regime. In addition, technological advancements in data analysis tools have motivated healthcare community to create precision-based therapies from surplus, available DNA data.

Advancements in genomics and associated technologies has significantly impacted crop genetics. Technological advancements in sequencing facilitates genomes & transcriptomes sequencing for several crops. Although a reference genome exists for several crops, resequencing and gene expression studies are required for in-depth study of key genes contributing to the desired trait. Implementation of this information in crop breeding helps in development of advanced crops.

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The companies are involved in strategic alliances with global as well as local entities to boost their revenue generation and enhance their share in the market. For instance, in March 2017, Foundation Medicine collaborated with Bristol-Myers Squibb Company, as a result of which Bristol-Myers Squibb could deploy Foundation Medicine's molecular information solutions and comprehensive genomic profiling for identification of predictive biomarkers, such as Microsatellite Instability (MSI) and Tumor Mutational Burden (TMB), to accelerate its immunotherapy clinical trials. Such initiatives are aimed at increasing the adoption of genomic information in cancer management.

Further key findings from the report suggest:
  • High volume requirement and the high cost of specific reagents contribute to substantial revenue share. Companies are embracing the trend of offering varied reagents that simplify workflow process
  • NGS-based services held a major share in the genomics services segment due to its rapid adoption of whole genome sequencing and application of sequence databases for disease screening and prognosis
  • The demand for these services would remain strong with the expansion of the customer base from being limited to academic and research centers to CROs, biotech and pharma players.
  • Biomarkers exhibit high clinical potential and efficiency across treatment of wide range of diseases
  • Use of predictive biomarkers for diagnosis and monitoring take cancer eradication a step further. Moreover, organizations and programs such as National Biomarker Development Alliance (NBDA) are actively participating in development of novel biomarkers for cancer diagnosis
  • Thus biomarkers are expected to exhibit the fastest growth in the coming years over the forecast period
  • The growing interest of pharmaceutical and biotechnology companies in genomics is expected to drive market growth in the coming years.
  • As patients are focusing on their health, Direct-To-Consumer (DTC) laboratory testing is increasingly being employed. DTC genetic tests enable consumers to access information about their genetics without necessarily including healthcare professionals in the process.
  • A few emerging and established companies are competing in this space
  • Asia Pacific is the most potential region and an emerging market for genomics. This market is anticipated to grow at the highest CAGR of 12.7%.
  • Developing infrastructure in these countries has led to the increased demand for biomarkers for diagnostics purposes.
  • Major players include BGI; Agilent Technologies; Thermo Fisher Scientific, Inc.; Bio-Rad Laboratories, Inc; Foundation Medicine, Inc, 23andMe, Inc, Danaher, Illumina, Inc; Pacific Biosciences; Oxford Nanopore Technologies.; F. Hoffmann-La Roche Ltd., and Myriad Genetics, Inc.
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Bathroom and toilet assist devices : Aging demographics has created a demand for old-age homes and long-term care centers

The global bathroom and toilet assist devices market size is expected to reach USD 6.0 billion by 2025 at a 6.2% CAGR. Growth in prevalence of chronic diseases, coupled with aging population, has resulted in a rise in individuals with various disabilities. This has significantly driven the global market.

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Aging demographics has created a demand for old-age homes and long-term care centers, both of which drive demand for bathroom and toilet assist devices. In addition, rising disposable income and government support toward home healthcare is supporting market growth.

On the other hand, longer product life cycle is primarily challenging the growth of the market. In addition, reusability of these devices is restraining revenue generation. However, growth in demand for these devices is predicted to lower the effect of the above-mentioned factors.

Further key findings from the report suggest:
  • Commodes emerged as the largest product segment as a result of the many benefits offered such as improved adjustability, enhanced ease, and flap on seats
  • Bath lifts and aids form the fastest growing segment owing to increase in number of patients with spinal injuries, which has spurred demand for various forms of mobility assist devices
  • North America dominated the market in terms of revenue in 2016. Improved awareness regarding commercially available assist devices and increasing disposable income are propelling revenue generation in the region
  • Europe is projected to witness swift growth during the forecast period owing to speedy adoption of advanced bathroom and toilet assist devices for patients with disabilities, to facilitate and reduce mobility issues
  • Key players include ArjoHuntleigh; Medical Device Depot; Carex Health Brands; Juvo Solutions; Bischoff & Bischoff GmbH; Invacare Corporation; Prism Medical; Sunrise Medical LLC; and GF Health Products, Inc.

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