Thursday 5 January 2017

Ensemble Therapeutics : Beyond Traditional Small Molecule Therapies

Focused on the discovery & development of small molecule therapies for patients, Ensemble Therapeutic Corporation is dedicated to offering effective & safer treatments for cancer & other grave diseases.

The company furiously applies its proprietary drug discovery platform and drug discovery experience to introduce small molecule treatments. It does so with the intention of challenging disease targets that are not effectively treated by regular antibodies or small molecules.


Small Molecule Treatments - Trends

The company mainly focuses on immuno-oncology programs that involve Indoleamine 2, 3-dioxygenase 1 (IDO-1). It provides inhibitors of apoptosis proteins, such as cIAP & XIAP - a group of tumor-promoting proteins that slow down the death of tumor cells by binding with enzymes that cause apoptosis. Ensemble is the first firm to exploit artificial macrocycle drugs (Ensemblins™) reliably & effectively.

Its synthetic macrocycle drugs possess distinctive qualities to address some ‘hard-to-address’ drug targets that are well-known to have key positions in ailment processes. With various matchless biological & chemical features, Ensemblins are a new category of drugs in the upcoming therapeutic space between biologics & small molecules.

Market  - Overview

Biopharmaceuticals are drugs for clinical purposes and produced by the extraction of nucleic acids & proteins directly from biological sources with the help of biotechnology. Most of the biopharmaceuticals are derived from genetically tailored animals & plants, also referred to as transgenic organisms. However, this is a controversial procedure and in the trial phase.

Growing elderly population, along with rising awareness & healthcare expenditures are the key drivers of the global biopharmaceuticals market. North America is predicted to capture the highest shares in the near future. Asia Pacific should record the highest expansion. Its unexploited prospects can account for regional growth. Some players in the worldwide industry comprise Merck & Co. Inc.; Pfizer Inc.; Novartis A. G.; and GlaxoSmithKline PLC.

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